Standard Operating Procedure (SOP)


The Laboratory Standard, under the provisions of the Chemical Hygiene Plan, requires standard operating procedures (SOPs) be established for work with hazardous chemicals: "Standard operating procedures relevant to safety and health considerations must be followed when laboratory work involves the use of hazardous chemicals.” All lab personnel, who perform hazardous operations, need to document that they have read and understand all SOPs relevant to their research. New students/employees shall be given hands-on training by their supervisor for hazardous operations which should include all relevant SOPs.

Standard Operating Procedure

  • UCSF requires investigators who work with hazardous chemicals to log in to RIO to upload SOP.
  • SOPs are written instructions that detail the requirements for working with hazardous chemicals and/or processes.
  • All SOP templates used is approved by the USCF Chemical Environmental Safety Committee (CESC) for work with hazardous chemicals.

At UCSF, a standard operating procedure can be found within the EHS webpage. SOPs must be developed, reviewed, approved, and confirmed before using chemicals.

Particularly hazardous substances

Particularly hazardous substances include (but is not limited to) select carcinogens, reproductive toxins, and substances which have a high degree of acute toxicity. Provisions for additional employee protection are required for work with particularly hazardous substances.

Important – For all work with particularly hazardous substances, the PI / lab supervisor must complete an appropriate Standard Operating Procedure, including:

  • Carcinogens
  • Reproductive hazards
  • Acutely toxic materials

Provisions for additional employee protection for work with particularly hazardous substances. These include "select carcinogens," reproductive toxins and substances which have a high degree of acute toxicity. Specific consideration shall be given to the following provisions which shall be included where appropriate;

1. Establishment of a designated area;
2. Use of containment devices such as fume hoods or glove boxes;
3. Procedures for safe removal of contaminated waste; and
4. Decontamination procedures.